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In patients, the concomitant administration of digoxin with dofetilide was associated with a higher occurrence of torsade de pointes. !–more– a rel=nofollow href=http://QualityDrugs.netimg alt=Buy Digoxin online src=http://QualityDrugs.net/QualityDrugs.png width=100%/a center a...

In patients, the concomitant administration of digoxin with dofetilide was associated with a higher occurrence of torsade de pointes.
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more info needed but, digoxin is definitely not a first line drug that cardiologists go to these days as there are many better drugs we have in our armamenterium nowadays.
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drugs that increase the serum digoxin concentration by decreasing intestinal motility and increasing absorption .
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digoxin is a substrate for p-glycoprotein pgp and clarithromycin is known to inhibit pgp.
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erythromycin; sulfisoxazole major the addition of erythromycin to digoxin therapy may lead to a significant increase 43-116 in serum digoxin concentration.

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